# Segment 13. The Yeast Genome

## Contents

#### Watch this segment

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Links to the slides: PDF file or PowerPoint file

Link to the file mentioned in the segment: SacSerChr4.txt

Link to all yeast chromosomes: UCSC

### Problems

#### To Calculate

1. With p=0.3, and various values of n, how big is the largest discrepancy between the Binomial probability pdf and the approximating Normal pdf? At what value of n does this value become smaller than $-15$ ?

2. Show that if four random variables are (together) multinomially distributed, each separately is binomially distributed.

2. Suppose that a Bayesian thinks that the prior probability of the hypothesis that "Failed to parse (unknown error): P_A=P_T " is 0.9, and that the set of all hypotheses that "Failed to parse (unknown error): P_A\ne P_T " have a total prior of 0.1. How might he calculate the odds ratio $Prob}(P_A=P_T)/\text{Prob$ ? Hint: Are there nuisance variables to be marginalized over?